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Merle Ruberg Selected Research

Herbal Teas

1/2004Annonacin, a lipophilic inhibitor of mitochondrial complex I, induces nigral and striatal neurodegeneration in rats: possible relevance for atypical parkinsonism in Guadeloupe.

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Merle Ruberg Research Topics

Disease

6Spinocerebellar Ataxias (Spinocerebellar Ataxia)
11/2014 - 08/2004
5Parkinsonian Disorders (Parkinsonism)
11/2008 - 01/2002
4Parkinson Disease (Parkinson's Disease)
01/2007 - 09/2003
3Tauopathies
11/2009 - 11/2005
3Neurodegenerative Diseases (Neurodegenerative Disease)
07/2007 - 11/2005
2Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome)
04/2009 - 11/2005
2Dementia (Dementias)
11/2008 - 08/2003
2Hereditary Spastic Paraplegia
08/2007 - 04/2007
1Autism Spectrum Disorder
12/2015
1Multiple Sclerosis
06/2013
1autosomal dominant Spastic paraplegia 3
09/2009
1Paraplegia (Spastic Paraplegia)
09/2009
1Myoclonus (Nocturnal Myoclonus)
11/2008
1REM Sleep Behavior Disorder
11/2008
1Hallucinations (Hallucination)
11/2008
1Tremor (Tremors)
11/2008
1Mitochondrial Diseases (Mitochondrial Disease)
05/2008
1Mood Disorders (Mood Disorder)
06/2007
1Type 4B1 Charcot-Marie-Tooth disease
05/2007
1Alzheimer Disease (Alzheimer's Disease)
06/2006
1Myoclonic Epilepsies (Myoclonic Encephalopathy)
04/2006
1Inborn Genetic Diseases (Disease, Hereditary)
03/2006
1Pheochromocytoma
04/2005
1Cerebellar Ataxia (Dysmetria)
08/2004
1Epilepsy (Aura)
04/2004
1Cognitive Dysfunction
08/2003
1Abnormal Reflex (Hyperreflexia)
08/2003
1Dystonia (Limb Dystonia)
08/2003
1Carcinogenesis
07/2002

Drug/Important Bio-Agent (IBA)

6Proteins (Proteins, Gene)FDA Link
11/2014 - 06/2003
4polyglutamineIBA
11/2014 - 03/2006
4annonacinIBA
11/2009 - 01/2004
4Levodopa (L Dopa)FDA LinkGeneric
11/2008 - 01/2002
3Ataxin-7IBA
11/2014 - 03/2007
3SpastinIBA
08/2007 - 08/2003
3AcetogeninsIBA
07/2007 - 01/2004
1Basic Amino Acid Transport SystemsIBA
12/2015
1AtaxinsIBA
06/2013
1CytokinesIBA
06/2013
1Interferon-betaIBA
06/2013
1Nuclear Proteins (Protein, Nuclear)IBA
06/2013
1LipidsIBA
09/2009
1Dynamins (Dynamin)IBA
09/2009
1GTP Phosphohydrolases (GTPases)IBA
09/2009
1Phosphates (Orthophosphate)IBA
04/2009
1NeurosteroidsIBA
05/2008
1CholesterolIBA
05/2008
1Carisoprodol (Soma)FDA LinkGeneric
07/2007
1Adenosine Triphosphate (ATP)IBA
07/2007
1myotubularinIBA
05/2007
1Histones (Histone)IBA
03/2007
1Oxidopamine (6 Hydroxydopamine)IBA
01/2007
11- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA
01/2007
1dexefaroxanIBA
06/2006
1Voltage-Gated Sodium ChannelsIBA
04/2006
1polyalanineIBA
03/2006
1RotenoneIBA
11/2005
1tau Proteins (tau Protein)IBA
11/2005
1alpha-SynucleinIBA
11/2005
1CalciumIBA
04/2005
1protein kinase C gamma (PRKCG)IBA
08/2004
1Ion Channels (Ion Channel)IBA
04/2004
1Neurotransmitter Receptors (Neurotransmitter Receptor)IBA
04/2004
1Anticonvulsants (Antiepileptic Drugs)IBA
04/2004
1Herbal TeasIBA
01/2004
1Proteasome Endopeptidase Complex (Proteasome)IBA
09/2003
1Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA
06/2003
1N-acetylsphingosineIBA
07/2002
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
07/2002

Therapy/Procedure

1Therapeutics
06/2007
1Denervation
09/2004